BSC’s spinoff company ELEM Biotech is born to commercialize on a Cloud-Deployed Software-as-a-Service basis the use of the HPC-based simulation code Alya for biomedical research. ELEM will become a Virtual Humans Factory, where in-silico trials can be performed thanks to a specifically designed user interface. Although ELEM’s first target will be the cardiovascular and respiratory…
A Mechanistic Model for Predicting Cell Surface Presentation of Competing Peptides by MHC Class I Molecules Denise S. M. Boulanger (1), Ruth C. Eccleston (2,3), Andrew Phillips (4), Peter V. Coveney (2,3,) Tim J. Elliott (1) and Neil Dalchau (4) 1 Centre for Cancer Immunology and Institute for Life Sciences, Faculty of Medicine, University of…
HITS researcher Dr Kashif Sadiq explores ribonucleoprotein granules, a condensed form of bio-matter found inside cells. He investigates whether the rate of enzymatic reactions in these membrane-less granules is accelerated. If true, this would lead to new insights in how cells regulate their biochemistry and may shed light on the origins of life on Earth.…
A recent paper published through a collaboration of our coordinator, UCL, with our Associate Partner at the Centre for Medical Informatics at the University of Edinburgh, outlines the use and release of the PolNet software tool. https://doi.org/10.1016/j.bpj.2018.03.032 PolNet is a software tool for the computer simulation of blood flow in realistic microvascular networks imaged with…
The course is organised and funded by BioExcel – the Centre of Excellence for Computational Biomolecular Research (http://bioexcel.eu), and PRACE, and delivered in collaboration with ARCHER – the UK national supercomputing service (http://archer.ac.uk)
At the University of Oxford, in the group of Professor Blanca Rodriguez and Dr Alfonso Bueno-Orovio, Dr Elisa Passini has won the International 3Rs Prize for computer modelling that predicts human cardiac safety better than animal studies. Their winning paper, in collaboration with Janssen Pharmaceutica describes the use of human-based computer models that have proven…
Leibniz Supercomputing Centre (LRZ) have announced that they have signed a contract with Intel and Lenovo to build SuperMUC-NG, which will be the next generation of their supercomputers. SuperMUC-NG will be capable of 26.7 petaflops at its theoretical peak, representing a five-fold increase in computing power over the current SuperMUC machine at LRZ. The leadership…
In Dan Brown’s fifth instalment of his Robert Langdon series, the hero finds himself in Barcelona whilst searching for a cryptic password and evading an enemy, determined to kidnap him. As part of this thrilling story they mention Barcelona Supercomputing Centre several times and also draw attention to the beautiful Marenostrum supercomputer. In the extract…
The INtegrated and Scalable PredictIon of REsistanace (INSPIRE) project aims to lay the foundations for the use of molecular simulation and machine learning to guide precision cancer therapy, in which therapy is tailored to provide maximum benefit to individual patients based on the genetic information about their particular cancer. In recent years, the development of…
Prof Peter V Coveney (UCL) has acted as a Program Reviewer for the Helmholtz Association in Germany. Between 23-26 October, he evaluated the work of Forschungszentrum Jülich (FZJ) with a specific remit to review their work in their domain entitled “Decoding the Human Brain”. The Forschungszentrum Jülich conducts research to provide comprehensive solutions to the…